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Collectively in light of the above
2018-11-01
Collectively, in light of the above results, both increase/restoration of the homeostatic cutaneous eCB-tone by FAAH-inhibitors and topical administration of non-psychotropic pCBs hold out the promise to exert remarkable anti-inflammatory actions, making them very exciting drug candidates, deserving
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A number of clinical proteomics studies have generated a
2018-11-01
A number of clinical proteomics studies have generated a long list of candidate urine protein biomarkers of various diseases (Beretov et al., 2015; Goodison et al., 2009; Rodriguez-Suarez et al., 2014; Shao, 2015); however, no biomarkers derived from ‘discovery’ studies were successfully translated
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Dysregulation or mutations of catenin are widespread in
2018-11-01
Dysregulation or mutations of β-catenin are widespread in GIC, and altered β-catenin plays fundamental roles in GIC initiation and progression (Basu et al., 2016; Oguma et al., 2008; Vogelstein et al., 2013). By interacting with β-catenin, ASF1A thus exhibits multiple oncogenic activities, as docume
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La Hip tesis del Estancamiento Secular
2018-11-01
La Hipótesis del Estancamiento Secular (secular stagnation hypothesis, ssh de aquí en adelante), fue planteada por primera vez por el profesor de Harvard, Alvin Hansen, en su trabajo “Economic Progress and Declining, quien sostuvo que por determinadas características estructurales (como la reducción
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Data Silver resistance genes are part of
2018-11-01
Data Silver resistance genes are part of a plasmid-associated gene cluster that encodes a silver binding protein (silE), efflux pump (silA and silP), and a membrane sensor kinase (silS) [2]. Melting curve analysis was performed to determine the specificity of the PCR products for the silver resista
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Tunicamycin br Acknowledgements The authors thank the
2018-11-01
Acknowledgements The authors thank the framework agreement between the Universidad Nacional de Colombia and Universidad de los Andes (Bogotá, Colombia) under which this work was carried out. They also wish to thank the Bank of the Republic of Colombia and Project 3580 for funding this research.
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The results of the current year follow up study demonstrate
2018-11-01
The results of the current 12-year follow up study demonstrate continuity of intervention effects that were found at 8 years. When children were observed at age 8 those placed into foster care before 24 months were indistinguishable to never institutionalized children in alpha power (Vanderwert et a
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Why was the model able to capture these
2018-11-01
Why was the model able to capture these qualitative effects? That is, what was the mechanistic account of the empirical data? In the model, there is experimental control over the constraints that shape development. We can therefore plot predictive power of these constraints across development, split
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br Materials and methods br Results br Discussion In the
2018-11-01
Materials and methods Results Discussion In the entire sample, we found a significant effect of NLT but not WMT, although there was a trend for the typically developing group (p=0.08). Training using the number-line thus transferred to mathematical tests without a number-line. This study di
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br Results and discussion br Conclusions The
2018-11-01
Results and discussion Conclusions The electronic structures, elastic properties and thermodynamics of MgZn2, Mg2Y and Mg2La were determined from first-principles calculation. The calculated heats of formation and cohesive energies show that Mg2La has the strongest alloying ability and structu
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br Case report She presented with gradually
2018-11-01
Case report She presented with gradually enlarging masses over the groin, which had been evident for 2 months. Physical examination revealed several movable, elastic-firm nodules (1–2 cm in diameter) without tenderness over the bilateral inguinal areas (Figure 1A). Erosive wounds and flaccid bull
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The malignant tumors are mostly circumscribed multinodular l
2018-11-01
The malignant tumors are mostly circumscribed, multinodular lesions which tend to recur as bulky nodules and metastasize after years or decades. However, factors affecting the risk and onset of malignant NCH transformation are still unknown. The time period for malignant tumor development has been e
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The eczematous dermatitis group includes contact
2018-11-01
The eczematous dermatitis group includes contact dermatitis, neurodermatitis, nummular eczema, and seborrheic dermatitis. Contact dermatitis has two subtypes: allergic contact dermatitis and irritant contact dermatitis. Individuals\' sensibility, in the elderly population, to allergic contact dermat
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The coatings were subjected to face
2018-11-01
The coatings were subjected to face bend test by three point bend test as per ASTM-E190, AWSB4.0 guided bend test. Samples after testing are shown in Fig. 6. Bending was discontinued at the instant of pealing or cracking of the coating. From the bend sample the radius of bend was obtained to estimat
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The product development task for this
2018-11-01
The product development task for this life-saving pyrotechnic product must be to get as much gas as possible in shortest possible time. Correct formula writing has now led us to a question that must have a rational answer, viz., why is the iron oxide there? A possible answer may be that it acts as a
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