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Finally in the context of
2018-10-23
Finally, in the context of this adipose specific FABP4 transgenic (over expression) mouse model phenotype, it is essential to discuss the caveats of this animal model. In the last five years several reviews have highlighted the advantages and disadvantages of the different promoters (for example FAB
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Early trials on the mg kg dose reported
2018-10-23
Early trials on the 0.75mg/kg dose reported variable reductions in gametocyte carriage (El-Sayed et al., 2007; Shekalaghe et al., 2011; von Seidlein et al., 2003) and a dose-ranging trial in clinically ill patients showed efficacy at doses as low as 0.40mg/kg (Eziefula et al., 2014a); however, non-i
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br Materials and Methods br
2018-10-23
Materials and Methods Results Discussion We sought to define properties of anti-Env Abs critical for mucosal HIV-1 protection, addressing two major issues in the vaccine field: the need to prioritize induction of IgA rather than IgG, and broadly-neutralizing activities rather than other ant
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In conclusion the present study provides the comprehensive e
2018-10-23
In conclusion, the present study provides the comprehensive examination of the beneficial consequences of therapeutic doses of metformin in the PCOS-like rat uterus (Fig. 8). Strategies to treat PCOS-related reproductive disturbances, including long-term treatment with metformin, remain unstandardiz
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Yang et al now show that fluvastatin inhibits lung cancer
2018-10-23
Yang et al. now show that fluvastatin inhibits lung cancer bone metastasis by triggering autophagy in lung cancer Y-27632 (). It was documented that fluvastatin inhibits migration and invasion by human lung cancer cells without significantly affecting proliferation and inhibits bone metastasis of t
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BLZ945 As one of KLF family members KLF was discovered as
2018-10-23
As one of KLF family members, KLF15 was discovered as kidney-enriched KLF, so called as KKLF (). Emerging evidence demonstrates the importance of KLF15 in various physiological and pathophysiological aspects. The physiological functions include the important role in regulating the expression of gen
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Furthermore there are no studies exploring
2018-10-23
Furthermore, there are no studies exploring if additional anti-anaerobic therapy improves DFI outcome, and in this study, we find no correlation between the high relative abundance of obligate anaerobes and a greater tendency to fail antimicrobial therapy. The decision to use targeted antimicrobials
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Mechanistically the age promoting effects of senescence are
2018-10-23
Mechanistically, the age-promoting effects of senescence are associated with the restriction of regenerative capacity of stem and progenitor boldenone undecylenate (Choudhury et al., 2007; Jurk et al., 2014) as well as the secretion of bioactive molecules (the so-called SASP (Coppe et al., 2008)),
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Loss of the first phase insulin response is
2018-10-23
Loss of the first phase insulin response is believed to be the first detectable defect in beta-cell function (), thus men with optimal glucose regulation were at increased risk of cancer relative to those with less rapid glucose clearance. This is in contrast to most of the literature linking diabet
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br Data sets and attributes The data published here are
2018-10-23
Data sets and attributes The data published here are organized in two ‘csv’ files, ‘rawdata.csv.gz’ (4.5MB) and ‘features.csv’ (200kB). The raw data are stored in the first file ‘rawdata.csv.gz’, where each line represents a single measurement per sensor. Consequently, one needs to read specific
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In vehicle structures the majority of the adhesive bonded
2018-10-22
In vehicle structures, the majority of the adhesive-bonded components is exposed to the environment of temperature and moist air. Previous studies revealed that if the exposure was over a significant period of time, the joint strength gradually declined [6] which was closely related to the water ang
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Introduction The electromagnetic railgun EMG is composed of
2018-10-22
Introduction The electromagnetic railgun (EMG) is composed of rails, armature, insulators and containment [1–3]. The armature can be sped up to 2 km/s by feeding the exciting current to the breech of railgun [4,5]. However, ablation occurs frequently on the rails during experiments. Researches show
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A pesar de la disminuci n del activismo l sbico
2018-10-22
A pesar de la disminución del activismo lésbico-gay durante la década de 1980, debido fairly factores como la crisis económica, la epidemia de sida, el desgaste de las y los activistas y los conflictos internos, el movimiento mexicano lésbico-gay continuó trabajando de forma internacional, particula
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Para entender c mo se involucran los actores
2018-10-22
Para entender cómo se involucran los actores en la contienda, parto de la idea foucaultiana de que los sujetos son producto de discursos y desde su subjetividad ejecutan actos de habla que producen efectos (Butler, 2004, p. 18). En esta disputa, los actores se movilizan mediante el uso de discursos
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Guggul is a natural gum resin which is obtained from
2018-10-22
Guggul is a natural gum resin which is obtained from plant Commiphora Mukul or Commiphora Wightii belonging to family Burceacea. This oleo gum resin is generally used in Ayurvedic formulations for treatment of obesity, inflammation, rheumatism, acne, arthrosclerosis etc. The purpose of using guggul
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