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In a previous paper we
2021-10-11
In a previous paper, we demonstrated immunohistochemically the amiodarone hcl of GHSR-1a in acrosomes and peripheral region of spermatid heads as well as in acrosomes of the spermatids undergoing spermiation [19]. The present study was undertaken to demonstrate the GHSR-1a expression in rat epididy
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Experiments show that CSD propagation can be slowed or
2021-10-11
Experiments show that CSD propagation can be slowed or interrupted by pre-existing lesions or areas of high astrocytic density (Chen et al., 2006), and reduced expression of astrocytic gap junctions significantly increases the size of ischemic infarcts (Nakase et al., 2003). By decreasing the gap ju
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Syringe services programs SSPs as
2021-10-11
Syringe services programs (SSPs), as well as expanded HIV and hepatitis C virus (HCV) testing, are key components of harm reduction for PWID and can reduce HIV and hepatitis C virus (HCV) transmissions in this 1423 [14], [15], [16]. The number of SSPs has increased in recent years in West Virginia
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TRRAP participates in embryonic development as demonstrated
2021-10-11
TRRAP participates in embryonic development, as demonstrated by its binding with proteins regulating the Notch signaling pathway in fruit fly, the Ras signaling pathway in C. elegans, or the Wnt signaling pathway in 293T cells. Therefore we suspect that TRRAP variants, more especially those falling
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2801 australia Ras small GTPases are critical
2021-10-11
Ras small GTPases are critical molecular switches that connect extracellular signals to intracellular signaling pathways initiated by membrane receptors, such as growth factor receptors and G protein-coupled receptors (Simanshu et al., 2017). When shifting between active GTP-bound and inactive GDP-b
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br Conflict of interest statements br Acknowledgements br In
2021-10-11
Conflict of interest statements Acknowledgements Introduction Oral squamous cell carcinoma (OSCC) is the sixth most common cancer worldwide and is the major cause for cancer morbidity and mortality in developing countries. Age standardized incidence rate in India is 12.6 per 100 000 populat
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br Discussion Recent progresses in osteoblast biology
2021-10-11
Discussion Recent progresses in osteoblast biology reveal that aerobic glycolysis was the main pathway to supply energy and materials that need by osteoblast differentiation [3]. In current study, we showed that LA enhanced the effect of PTH on osteblast differentiation and revealed an unrecogniz
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Using RT PCR we demonstrated the
2021-10-11
Using RT-PCR we demonstrated the expression of GPR55 receptor mRNA in the ileum and colon of mice, which is in good agreement with previous reports (Lin et al., 2011). The quantitative analysis showed the abundance of GPR55 mRNA in the mucosa of the ileum and colon. In contrast, in LMMP preparations
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br Synthetic Antagonists for FFA
2021-10-11
Synthetic Antagonists for FFA4 To date, only compounds from a single chemical series have been reported as FFA4 ‘antagonists’ (Table 1). ‘Compound 39’ (4-methyl-N-9H-xanthen-9-yl-benzenesulfonamide), now available from commercial vendors as AH-7614, was initially reported as an antagonist at this
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One of the possible disadvantages of this methodology
2021-10-11
One of the possible disadvantages of this methodology is a possible cytotoxic effect resulting from either adenoviral vector injection or to Cre recombinase expression. Adenovirus has previously been used to efficiently mediate transgene expression in mouse sphingosine (Thomas et al., 2000, Xia et
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br Material and methods br Results
2021-10-11
Material and methods Results Discussion Organisms have developed a variety of anti-glycation defense mechanisms. In flecainide acetate to the aldose-reductase-pathway or 2-oxoaldehyde dehydrogenase-pathway, the glyoxalase system is the only mechanism, which is not restricted to liver [19].
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Our results indicate that abcb is likely to be a
2021-10-11
Our results indicate that abcb5 is likely to be a XT in zebrafish ionocytes, although, like renal cells, the phenotypes observed likely arise from the action of multiple transporters. Zebrafish lack an abcb1 ortholog, and abcb4 and abcb5 have been identified as the P-glycoproteins in zebrafish (Fisc
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Introduction Human pathogenic Leishmania protozoa comprise
2021-10-11
Introduction Human pathogenic Leishmania protozoa comprise 20 different species that are distributed throughout the world and cause the disease leishmaniasis [1]. Transmission primarily occurs through the bite of a female sand fly and clinical manifestations of the disease span from cutaneous lesio
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The NVC response in the diseased or aging brain may
2021-10-11
The NVC response in the diseased or aging Cy5 azide synthesis may be altered, including changes in both the chemical mediators of NVC, ion channel behaviour, and the dynamics of the vascular system. For example, in Alzheimer’s disease the production of NO is shown to be inhibited (Lourenço et al., 2
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In summary two new flexible amine functionalized quinolinium
2021-10-09
In summary, two new flexible amine-functionalized quinolinium derivatives with far-red region emitting were prepared. The shorter-chain fatty amine side chain in the scaffold of was found to be a more promising G-quadruplex DNA fluorescent probe, suggesting the amine side group plays an important ro
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