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Comparative analysis of transgenic hPAX
2018-11-08
Comparative analysis of transgenic hPAX6GFP expression revealed similarities between the retinal organoid system and the mouse retina in vivo. Our analyses indicated a similar sequence of hPAX6GFP+ retinal cell types in mice in vivo, and in mESC- and hESC-derived retinal organoids: progenitors and r
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br Introduction Meiosis is the key step of gametogenesis
2018-11-08
Introduction Meiosis is the key step of gametogenesis, which ensures the production of haploid gametes from their diploid precursors and the recombination of genetic materials from the parents. For lower eukaryotes such as yeasts, meiosis is initiated under unfavorable environmental conditions wh
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Several geographical factors appear to
2018-11-07
Several geographical factors appear to have an influence on circadian preferences. For instance, a marked delay in diurnal activities was observed in local young people when moving from East to West, from South to North and from towns to villages within the same time zone in the Russian Federation [
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Estos hechos indican que los pa ses
2018-11-07
Estos hechos indican que los países de la Unión se mantenían dentro de los “límites” de un endeudamiento “manejable”, implicando un alto riesgo frente angiotensin receptor blocker circunstancias externas (choques externos) como una crisis que dificulte el control gubernamental sobre tales variables,
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It is important to note that Marco
2018-11-07
It is important to note that Marco does not account for all of the monocyte inflammation caused by RSV infection. Targeted deletion of Marco significantly increased susceptibility to some RSV-induced phenotypes but did not account for all of the genetic variation identified by the strain screen. The
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angiotensin receptor blockers There are additional important
2018-11-07
There are additional important noteworthy points. Although both retinal pigment epithelial angiotensin receptor blockers (RPE) and endothelial cells showed glucose induced reduction of miR15a and associated alteration, overexpression of miR15a in the endothelial cells (as Tie2 is not expressed in t
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Another potential advantage is that BM induced selectively a
2018-11-07
Another potential advantage is that BM32 induced selectively allergen-specific IgG responses but did not induce boosts of allergen-specific IgE production. In fact, allergen extract-based but also peptide-based vaccines have been shown to induce strong boosts of allergen-specific IgE production. For
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The results of the hierarchical regression suggest that coun
2018-11-07
The results of the hierarchical regression suggest that countries with higher mean years of schooling are less likely to report positive vaccine sentiment, however within a country those with some education hold more positive views on vaccine importance, effectiveness, and religious compatibility (t
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Among the participants in our study
2018-11-07
Among the 1303 participants in our study, 74% (n=964) reported xerostomia (Table 2). Xerostomia prevalence was highest among SS participants (87.4%, 95% CI: 84.8%–89.8%) followed by Sicca participants (72.4%, 95% CI: 67.4%–77.0%) and the ISS group (38.1%, 95% CI: 32.0%–44.4%). The absolute differenc
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br Declaration of Interests br Author Contributions br Ackno
2018-11-07
Declaration of Interests Author Contributions Acknowledgments This work was supported by the EU FP7 project TBIcare (Project ref. 270259; to M.O., D.M., and O.T.), by the GE-NFL Head Health Challenge I Award (grant no. 7620 to M.O. and T.H.), by personal EVO funding (Finland) (to J.P.P and
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The vast majority of malaria infections in low endemic
2018-11-07
The vast majority of malaria infections in low endemic settings are of low density (Imwong et al., 2016) but can contribute considerably to onward malaria transmission (Slater et al., 2015). However, the impact of current ACT and ACT-PQ on preventing onward malaria transmission from these low-densit
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Mutant Cav channels showed significant changes in their elec
2018-11-07
Mutant Cav3.2 channels showed significant changes in their electrophysiological properties. Cav3.21549Ile, similarly to Cav3.21549Val (Scholl et al., 2015), shows a significant shift in activation and inactivation properties towards more negative potentials. Consequently, Cav3.21549Ile is activated
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The increase in total cAMP level after
2018-11-07
The increase in total cAMP level after SRT1720 appears modest (~20–70% at 0.2–2.5μM SRT1720), but this is most likely an underestimation because cAMP exists in compartments (Mongillo et al., 2004); the cAMP level in the relevant compartments could be significantly higher than in the rest of the cell
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br Funding The work was financially supported by
2018-11-07
Funding The work was financially supported by the by grants from the Ministry of Science and Technology of the People\'s Republic of China (2014AA020524), the Special Research Fund of Ministry of Health for Non-Profit Sector (201302010), the National Nature Science Foundation (81302507), the Scie
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rac protein Ahora bien tal y como se muestra en
2018-11-07
Ahora bien, tal y como se muestra en la Imagen 1, el sistema tributario mexicano que funcionó desde 1917 hasta 1935 se conformaba de once grandes rubros fiscales cobrados y administrados por la shcp. En términos generales, cuando un contribuyente no atendía al pago de las contribuciones se le determ
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